A Comparison of Spectinomycin with Ceftriaxone as Treatment for Uncomplicated Gonorrhea
نویسندگان
چکیده
Objective: To compare the efficacy of spectinomycin with ceftriaxone as treatment for Uncomplicated Gonorrhea. Design Study: It was a cross-sectional survey. Place and Duration This study carried at Department Pharmacology DHQ Teaching Hospital kohat Khaleefa Gul Nawaz Bannu from March 2019 to march 2020. Patients Methods: For trial, 200 participants were enrolled. Two groups 100 patients each formed by randomly dividing patients. Injections (2 gm) (500 mg) administered intramuscularly Group A B, respectively. After 5 days, all underwent reexaminations, their clinical laboratory results noted reviewed. Results When spectinomycin, in (n = 100) indicated 95% full response, 3% partial 2% no reaction, but when given ceftriaxone, B 91% 6% response all. Furthermore, aetiology gonorrhoea infection is not statistically associated getting older. Conclusion: The cure rates are indistinguishable. However, may only be used cases resistance because it causes pain injection site, less effective pharyngeal gonorrhoea, contraindicated during pregnancy breast-feeding. Keywords: Neisseria Gonorrhea, Ceftriaxone, Spectinomycin
منابع مشابه
Comparison of spectinomycin hydrochloride and aqueous procaine penicillin G in the treatment of uncomplicated gonorrhea.
Men and women with uncomplicated gonorrhea were randomly assigned to receive aqueous procaine penicillin G (2,400,000 U for men; 2,400,000 U daily for 2 days for women) or spectinomycin hydrochloride (2.0 g for men; 4.0 g for women). Among men who returned for post-treatment evaluation within 10 days, treatment failures were noted among 16 (20.3%) of 79 men who received penicillin and 8 (9.5%) ...
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Beta-lactamase-negative Neisseria gonorrhoeae infections were treated with single-dose cefoperazone (0.5 or 1.0 g) or spectinomycin (2.0 g). Anogenital infections were cured in 36 (83%) of 43 volunteers given 0.5 g of cefoperazone, 61 of 61 volunteers given 1.0 g of cefoperazone, and 99 of 100 volunteers given spectinomycin. The cefoperazone geometric mean MIC for 242 isolates was 0.028 microgr...
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To the editor: We have read with interest the recent paper by Kubanova et al. in which they recommend the use of spectinomycin in case of difficulty to access ceftriaxone or in the presence of severe beta-lactam antimicrobial allergy [1]. Although we agree with most of the conclusions we would like to warn about the potential risks in cases of pharyngeal gonorrhoea. Spectinomycin is an aminogly...
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ژورنال
عنوان ژورنال: Pakistan Journal of Medical and Health Sciences
سال: 2022
ISSN: ['1996-7195']
DOI: https://doi.org/10.53350/pjmhs22168587